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Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork
Two models have been proposed for triggering release of the lagging strand polymerase at the replication fork, enabling cycling to the primer for the next Okazaki fragment—either collision with the 5′-end of the preceding fragment (collision model) or synthesis of a new primer by primase (signaling...
Autores principales: | Yuan, Quan, McHenry, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919610/ https://www.ncbi.nlm.nih.gov/pubmed/24234450 http://dx.doi.org/10.1093/nar/gkt1098 |
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