Cargando…
Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage
By transporting one DNA double helix (T-segment) through a double-strand break in another (G-segment), topoisomerase II reduces fractions of DNA catenanes, knots and supercoils to below equilibrium values. How DNA segments are selected to simplify the equilibrium DNA topology is enigmatic, and the b...
Autores principales: | Martínez-García, Belén, Fernández, Xavier, Díaz-Ingelmo, Ofelia, Rodríguez-Campos, Antonio, Manichanh, Chaysavanh, Roca, Joaquim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919613/ https://www.ncbi.nlm.nih.gov/pubmed/24185700 http://dx.doi.org/10.1093/nar/gkt1037 |
Ejemplares similares
-
Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA
por: Valdés, Antonio, et al.
Publicado: (2019) -
Carboxyl terminal domain basic amino acids of mycobacterial topoisomerase I bind DNA to promote strand passage
por: Ahmed, Wareed, et al.
Publicado: (2013) -
Two type I topoisomerases maintain DNA topology in human mitochondria
por: Menger, Katja E, et al.
Publicado: (2022) -
DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase
por: Fidalgo da Silva, Elizabeth, et al.
Publicado: (2007) -
The 3′–5′ proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases
por: Russell, Henry J., et al.
Publicado: (2009)