Cargando…

Prospective identification of parasitic sequences in phage display screens

Phage display empowered the development of proteins with new function and ligands for clinically relevant targets. In this report, we use next-generation sequencing to analyze phage-displayed libraries and uncover a strong bias induced by amplification preferences of phage in bacteria. This bias fav...

Descripción completa

Detalles Bibliográficos
Autores principales: Matochko, Wadim L., Cory Li, S., Tang, Sindy K.Y., Derda, Ratmir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919620/
https://www.ncbi.nlm.nih.gov/pubmed/24217917
http://dx.doi.org/10.1093/nar/gkt1104