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Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips

During vertebrate mitosis, the centromere-associated kinesin CENP-E transports misaligned chromosomes to the plus ends of spindle microtubules. Subsequently, the kinetochores that form at the centromeres establish stable associations with microtubule ends, which assemble and disassemble dynamically....

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Detalles Bibliográficos
Autores principales: Gudimchuk, Nikita, Vitre, Benjamin, Kim, Yumi, Kiyatkin, Anatoly, Cleveland, Don W., Ataullakhanov, Fazly I., Grishchuk, Ekaterina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919686/
https://www.ncbi.nlm.nih.gov/pubmed/23955301
http://dx.doi.org/10.1038/ncb2831