Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia

BACKGROUND: Anti-GD2 antibody is a proven therapy for GD2-postive neuroblastoma. Monoclonal antibodies against GD2, such as chimeric mAb ch14.18, have become benchmarks for neuroblastoma therapies. Pain, however, can limit immunotherapy with anti-GD2 therapeutic antibodies like ch14.18. This adverse...

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Detalles Bibliográficos
Autores principales: Terme, Mickaël, Dorvillius, Mylène, Cochonneau, Denis, Chaumette, Tanguy, Xiao, Wenhua, Diccianni, Mitchell B., Barbet, Jacques, Yu, Alice L., Paris, François, Sorkin, Linda S., Birklé, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919714/
https://www.ncbi.nlm.nih.gov/pubmed/24520328
http://dx.doi.org/10.1371/journal.pone.0087210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919714/
https://www.ncbi.nlm.nih.gov/pubmed/24520328
http://dx.doi.org/10.1371/journal.pone.0087210

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