A High-Content, Multiplexed Screen in Human Breast Cancer Cells Identifies Profilin-1 Inducers with Anti-Migratory Activities

Profilin-1 (Pfn-1) is a ubiquitously expressed actin-binding protein that is essential for normal cell proliferation and migration. In breast cancer and several other adenocarcinomas, Pfn-1 expression is downregulated when compared to normal tissues. Previous studies from our laboratory have shown t...

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Detalles Bibliográficos
Autores principales: Joy, Marion E., Vollmer, Laura L., Hulkower, Keren, Stern, Andrew M., Peterson, Cameron K., Boltz, R. C. “Dutch”, Roy, Partha, Vogt, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919756/
https://www.ncbi.nlm.nih.gov/pubmed/24520372
http://dx.doi.org/10.1371/journal.pone.0088350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919756/
https://www.ncbi.nlm.nih.gov/pubmed/24520372
http://dx.doi.org/10.1371/journal.pone.0088350

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