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eNOS-Dependent Antisenscence Effect of a Calcium Channel Blocker in Human Endothelial Cells

Senescence of vascular endothelial cells is an important contributor to the pathogenesis of age-associated vascular disorders such as atherosclerosis. We investigated the effects of antihypertensive agents on high glucose-induced cellular senescence in human umbilical venous endothelial cells (HUVEC...

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Detalles Bibliográficos
Autores principales: Hayashi, Toshio, Yamaguchi, Tomoe, Sakakibara, Yasufumi, Taguchi, Kumiko, Maeda, Morihiko, Kuzuya, Masafumi, Hattori, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919771/
https://www.ncbi.nlm.nih.gov/pubmed/24520379
http://dx.doi.org/10.1371/journal.pone.0088391