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Myosin Light Chain Kinase Expression Induced via Tumor Necrosis Factor Receptor 2 Signaling in the Epithelial Cells Regulates the Development of Colitis-Associated Carcinogenesis

It has been suggested that prolonged inflammatory bowel diseases (IBD) may lead to colitis-associated carcinogenesis (CAC). We previously observed that the NF-κB activation in colonic epithelial cells is associated with increased tumor necrosis factor receptor 2 (TNFR2) expression in CAC development...

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Detalles Bibliográficos
Autores principales: Suzuki, Masahiro, Nagaishi, Takashi, Yamazaki, Motomi, Onizawa, Michio, Watabe, Taro, Sakamaki, Yuriko, Ichinose, Shizuko, Totsuka, Mamoru, Oshima, Shigeru, Okamoto, Ryuichi, Shimonaka, Motoyuki, Yagita, Hideo, Nakamura, Tetsuya, Watanabe, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919773/
https://www.ncbi.nlm.nih.gov/pubmed/24520376
http://dx.doi.org/10.1371/journal.pone.0088369