P-glycoprotein Modulates Morphine Uptake into the CNS: A Role for the Non-steroidal Anti-inflammatory Drug Diclofenac

Our laboratory has previously demonstrated that peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp) that is endogenously expressed at the blood-brain...

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Detalles Bibliográficos
Autores principales: Sanchez-Covarrubias, Lucy, Slosky, Lauren M., Thompson, Brandon J., Zhang, Yifeng, Laracuente, Mei-Li, DeMarco, Kristin M., Ronaldson, Patrick T., Davis, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919782/
https://www.ncbi.nlm.nih.gov/pubmed/24520393
http://dx.doi.org/10.1371/journal.pone.0088516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919782/
https://www.ncbi.nlm.nih.gov/pubmed/24520393
http://dx.doi.org/10.1371/journal.pone.0088516

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