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P-glycoprotein Modulates Morphine Uptake into the CNS: A Role for the Non-steroidal Anti-inflammatory Drug Diclofenac

Our laboratory has previously demonstrated that peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp) that is endogenously expressed at the blood-brain...

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Detalles Bibliográficos
Autores principales:	Sanchez-Covarrubias, Lucy, Slosky, Lauren M., Thompson, Brandon J., Zhang, Yifeng, Laracuente, Mei-Li, DeMarco, Kristin M., Ronaldson, Patrick T., Davis, Thomas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919782/ https://www.ncbi.nlm.nih.gov/pubmed/24520393 http://dx.doi.org/10.1371/journal.pone.0088516

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