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HIV-1 Transcripts Use IRES-Initiation under Conditions Where Cap-Dependent Translation Is Restricted by Poliovirus 2A Protease

The 30 different species of mRNAs synthesized during the HIV-1 replication cycle are all capped and polyadenilated. Internal ribosome entry sites have been recognized in the 5′ untranslated region of some mRNA species of HIV-1, which would contribute to an alternative mechanism of initiation of mRNA...

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Detalles Bibliográficos
Autores principales: Amorim, Raquel, Costa, Sara Mesquita, Cavaleiro, Nathalia Pereira, da Silva, Edson Elias, da Costa, Luciana Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919812/
https://www.ncbi.nlm.nih.gov/pubmed/24520405
http://dx.doi.org/10.1371/journal.pone.0088619