Cargando…

Effects of thyroxin and donepezil on hippocampal acetylcholine content and syntaxin-1 and munc-18 expression in adult rats with hypothyroidism

Adult-onset hypothyroidism induces various impairments in hippocampus-dependent cognitive function, in which numerous synaptic proteins and neurotransmitters are involved. Donepezil (DON), an acetylcholinesterase inhibitor, has been shown to be efficient in improving cognitive function. The aim of t...

Descripción completa

Detalles Bibliográficos
Autores principales: WANG, NAN, CAI, YAOJUN, WANG, FEN, ZENG, XIANZHONG, JIA, XUEMEI, TAO, FANGBIAO, ZHU, DEFA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919934/
https://www.ncbi.nlm.nih.gov/pubmed/24520241
http://dx.doi.org/10.3892/etm.2014.1487