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Mechanisms underlying the biological changes induced by isocitrate dehydrogenase-1 mutation in glioma cells

Isocitrate dehydrogenase 1 (IDH1) mutation has been reported to be associated with an increased overall survival in patients with glioma in a number of studies. Previous studies have focused on the mutation rate and possible metabolic pathways of the mutated IDH1 gene. However, the effects of IDH1 m...

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Detalles Bibliográficos
Autores principales: WANG, JU-BO, DONG, DAN-FENG, GAO, KE, WANG, MAO-DE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919947/
https://www.ncbi.nlm.nih.gov/pubmed/24520288
http://dx.doi.org/10.3892/ol.2014.1806