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Mechanisms underlying the biological changes induced by isocitrate dehydrogenase-1 mutation in glioma cells
Isocitrate dehydrogenase 1 (IDH1) mutation has been reported to be associated with an increased overall survival in patients with glioma in a number of studies. Previous studies have focused on the mutation rate and possible metabolic pathways of the mutated IDH1 gene. However, the effects of IDH1 m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919947/ https://www.ncbi.nlm.nih.gov/pubmed/24520288 http://dx.doi.org/10.3892/ol.2014.1806 |