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Increased metal content in the TDP-43(A315T) transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Disrupted metal homeostasis is a consistent feature of neurodegenerative disease in humans and is recapitulated in mouse models of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and neuronal ceriod lipofuscinosis. While the definitive pathogenesis of neurodegenerative...

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Detalles Bibliográficos
Autores principales: Dang, Theresa N. T., Lim, Nastasia K. H., Grubman, Alexandra, Li, Qiao-Xin, Volitakis, Irene, White, Anthony R., Crouch, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920072/
https://www.ncbi.nlm.nih.gov/pubmed/24575040
http://dx.doi.org/10.3389/fnagi.2014.00015