Novel Class of Potential Therapeutics that Target Ricin Retrograde Translocation

Ricin toxin, an A-B toxin from Ricinus communis, induces cell death through the inhibition of protein synthesis. The toxin binds to the cell surface via its B chain (RTB) followed by its retrograde trafficking through intracellular compartments to the ER where the A chain (RTA) is transported across...

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Detalles Bibliográficos
Autores principales: Redmann, Veronika, Gardner, Thomas, Lau, Zerlina, Morohashi, Keita, Felsenfeld, Dan, Tortorella, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920248/
https://www.ncbi.nlm.nih.gov/pubmed/24366208
http://dx.doi.org/10.3390/toxins6010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920248/
https://www.ncbi.nlm.nih.gov/pubmed/24366208
http://dx.doi.org/10.3390/toxins6010033

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