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Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins. Microcystins have many structural variations, yet insufficient information is available on the differences in t...

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Detalles Bibliográficos
Autores principales: Shimizu, Kumiko, Sano, Tomoharu, Kubota, Reiji, Kobayashi, Norihiro, Tahara, Maiko, Obama, Tomoko, Sugimoto, Naoki, Nishimura, Tetsuji, Ikarashi, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920255/
https://www.ncbi.nlm.nih.gov/pubmed/24380975
http://dx.doi.org/10.3390/toxins6010168