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Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes
Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins. Microcystins have many structural variations, yet insufficient information is available on the differences in t...
Autores principales: | Shimizu, Kumiko, Sano, Tomoharu, Kubota, Reiji, Kobayashi, Norihiro, Tahara, Maiko, Obama, Tomoko, Sugimoto, Naoki, Nishimura, Tetsuji, Ikarashi, Yoshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920255/ https://www.ncbi.nlm.nih.gov/pubmed/24380975 http://dx.doi.org/10.3390/toxins6010168 |
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