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Src tyrosine kinase signaling antagonizes nuclear localization of FOXO and inhibits its transcription factor activity
Biochemical experiments in mammalian cells have linked Src family kinase activity to the insulin signaling pathway. To explore the physiological link between Src and a central insulin pathway effector, we investigated the effect of different Src signaling levels on the Drosophila transcription facto...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920272/ https://www.ncbi.nlm.nih.gov/pubmed/24513978 http://dx.doi.org/10.1038/srep04048 |