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Interaction of Memantine with Homocysteine on the Apoptosis in the Rat Hippocampus cells

It has been hypothesized that elevated plasma Homocysteine (Hcy) plays a role in the pathogenesis of Alzheimer’s disease (AD) and age-related cognitive decline. The mechanism of Hcy neurotoxicity in the brain is controversial as well Hcy is a ligand of NMDA receptor. Memantine, an uncompetitive anta...

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Detalles Bibliográficos
Autores principales: Ataie, Amin, Ataee, Ramin, Shadifar, Mohammad, Shahabi, Sima, Aghajanpour, Seyed Mohsen, Hosseinpour, Younes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920501/
https://www.ncbi.nlm.nih.gov/pubmed/24551770