Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation

Aberrant microglial responses contribute to neuroinflammation in many neurodegenerative diseases, but no current therapies target pathogenic microglia. We discovered unexpectedly that the antiviral drug ganciclovir (GCV) inhibits the proliferation of microglia in experimental autoimmune encephalomye...

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Detalles Bibliográficos
Autores principales: Ding, Zhaoqing, Mathur, Vidhu, Ho, Peggy P., James, Michelle L., Lucin, Kurt M., Hoehne, Aileen, Alabsi, Haitham, Gambhir, Sanjiv S., Steinman, Lawrence, Luo, Jian, Wyss-Coray, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920559/
https://www.ncbi.nlm.nih.gov/pubmed/24493798
http://dx.doi.org/10.1084/jem.20120696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920559/
https://www.ncbi.nlm.nih.gov/pubmed/24493798
http://dx.doi.org/10.1084/jem.20120696

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