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Memory CD8(+) T cells exhibit increased antigen threshold requirements for recall proliferation

A hallmark of immunological memory is the ability of previously primed T cells to undergo rapid recall responses upon antigen reencounter. Classic work has suggested that memory T cells proliferate in response to lower doses of antigen than naive T cells and with reduced requirements for co-stimulat...

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Detalles Bibliográficos
Autores principales: Mehlhop-Williams, Erin R., Bevan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920562/
https://www.ncbi.nlm.nih.gov/pubmed/24493801
http://dx.doi.org/10.1084/jem.20131271