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Memory CD8(+) T cells exhibit increased antigen threshold requirements for recall proliferation
A hallmark of immunological memory is the ability of previously primed T cells to undergo rapid recall responses upon antigen reencounter. Classic work has suggested that memory T cells proliferate in response to lower doses of antigen than naive T cells and with reduced requirements for co-stimulat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920562/ https://www.ncbi.nlm.nih.gov/pubmed/24493801 http://dx.doi.org/10.1084/jem.20131271 |