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2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8(+) T cell responses

Mounting evidence in models of both autoimmunity and chronic viral infection suggests that the outcome of T cell activation is critically impacted by the constellation of co-stimulatory and co-inhibitory receptors expressed on the cell surface. Here, we identified a critical role for the co-inhibito...

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Detalles Bibliográficos
Autores principales: Liu, Danya, Krummey, Scott M., Badell, I. Raul, Wagener, Maylene, Schneeweis, Lumelle A., Stetsko, Dawn K., Suchard, Suzanne J., Nadler, Steven G., Ford, Mandy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920565/
https://www.ncbi.nlm.nih.gov/pubmed/24493803
http://dx.doi.org/10.1084/jem.20130902