Cargando…
2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8(+) T cell responses
Mounting evidence in models of both autoimmunity and chronic viral infection suggests that the outcome of T cell activation is critically impacted by the constellation of co-stimulatory and co-inhibitory receptors expressed on the cell surface. Here, we identified a critical role for the co-inhibito...
Autores principales: | Liu, Danya, Krummey, Scott M., Badell, I. Raul, Wagener, Maylene, Schneeweis, Lumelle A., Stetsko, Dawn K., Suchard, Suzanne J., Nadler, Steven G., Ford, Mandy L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920565/ https://www.ncbi.nlm.nih.gov/pubmed/24493803 http://dx.doi.org/10.1084/jem.20130902 |
Ejemplares similares
-
Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression
por: Liu, Danya, et al.
Publicado: (2015) -
Selective CD28 blockade impacts T cell differentiation during homeostatic reconstitution following lymphodepletion
por: Habib, Jakob G., et al.
Publicado: (2023) -
CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells
por: Krummey, Scott M., et al.
Publicado: (2020) -
CD154 Blockade Alters Innate Immune Cell Recruitment and Programs Alloreactive CD8(+) T Cells into KLRG-1(high) Short-Lived Effector T Cells
por: Ferrer, Ivana R., et al.
Publicado: (2012) -
CD8+CD122+PD-1+ Tregs Synergize With Costimulatory Blockade of CD40/CD154, but Not B7/CD28, to Prolong Murine Allograft Survival
por: Liu, Huazhen, et al.
Publicado: (2019)