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Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

The erythroid stress cytokine erythropoietin (Epo) supports the development of committed erythroid progenitors, but its ability to act on upstream, multipotent cells remains to be established. We observe that high systemic levels of Epo reprogram the transcriptomes of multi- and bipotent hematopoiet...

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Detalles Bibliográficos
Autores principales: Grover, Amit, Mancini, Elena, Moore, Susan, Mead, Adam J., Atkinson, Deborah, Rasmussen, Kasper D., O’Carroll, Donal, Jacobsen, Sten Eirik W., Nerlov, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920567/
https://www.ncbi.nlm.nih.gov/pubmed/24493804
http://dx.doi.org/10.1084/jem.20131189