Cargando…
High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias
Hematopoietic stem cells (HSCs) are heterogeneous with respect to their self-renewal, lineage, and reconstitution potentials. Although c-Kit is required for HSC function, gain and loss-of-function c-Kit mutants suggest that even small changes in c-Kit signaling profoundly affect HSC function. Herein...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920569/ https://www.ncbi.nlm.nih.gov/pubmed/24446491 http://dx.doi.org/10.1084/jem.20131128 |