The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams

The increasing incidence of inducible chromosomal AmpC β-lactamases within the clinic is a growing concern because these enzymes deactivate a broad range of even the most recently developed β-lactam antibiotics. As a result, new strategies are needed to block the action of this antibiotic resistance...

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Detalles Bibliográficos
Autores principales: Stubbs, Keith A, Bacik, John-Paul, Perley-Robertson, G Evan, Whitworth, Garrett E, Gloster, Tracey M, Vocadlo, David J, Mark, Brian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920638/
https://www.ncbi.nlm.nih.gov/pubmed/24009110
http://dx.doi.org/10.1002/cbic.201300395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920638/
https://www.ncbi.nlm.nih.gov/pubmed/24009110
http://dx.doi.org/10.1002/cbic.201300395

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