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Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet

Rapamycin (RAPA) is a clinical immunosuppressive agent first reported in the literature in 1975 after its discovery in a soil sample from the island of Rapa Nui. Aside from the well-documented effects of RAPA on cell division and immunologic response, the literature reveals it to have negative effec...

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Detalles Bibliográficos
Autores principales: Ray, Peter D., Maclellan, Reid A., He, Jin, Liu, Zhigang, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920817/
https://www.ncbi.nlm.nih.gov/pubmed/24587943
http://dx.doi.org/10.1155/2014/540582