Rapamycin Attenuates Endothelial Apoptosis Induced by Low Shear Stress via mTOR and Sestrin1 Related Redox Regulation

Background. Studies indicate the dramatic reduction of shear stress (SS) within the rapamycin eluting stent (RES) segment of coronary arteries. It remains unclear about the role of rapamycin in endothelialization of stented arteries where SS becomes low. Since mTOR (mammalian target of rapamycin) pa...

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Detalles Bibliográficos
Autores principales: Zhang, Junxia, Wang, Zhimei, Zhang, Junjie, Zuo, Guangfeng, Li, Bing, Mao, Wenxing, Chen, Shaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920857/
https://www.ncbi.nlm.nih.gov/pubmed/24587596
http://dx.doi.org/10.1155/2014/769608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920857/
https://www.ncbi.nlm.nih.gov/pubmed/24587596
http://dx.doi.org/10.1155/2014/769608

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