Adipose Tissue-Derived Stem Cell Secreted IGF-1 Protects Myoblasts from the Negative Effect of Myostatin

Myostatin, a TGF-β family member, is associated with inhibition of muscle growth and differentiation and might interact with the IGF-1 signaling pathway. Since IGF-1 is secreted at a bioactive level by adipose tissue-derived mesenchymal stem cells (ASCs), these cells (ASCs) provide a therapeutic opt...

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Detalles Bibliográficos
Autores principales: Gehmert, Sebastian, Wenzel, Carina, Loibl, Markus, Brockhoff, Gero, Huber, Michaela, Krutsch, Werner, Nerlich, Michael, Gosau, Martin, Klein, Silvan, Schreml, Stephan, Prantl, Lukas, Gehmert, Sanga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920898/
https://www.ncbi.nlm.nih.gov/pubmed/24575400
http://dx.doi.org/10.1155/2014/129048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920898/
https://www.ncbi.nlm.nih.gov/pubmed/24575400
http://dx.doi.org/10.1155/2014/129048

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