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Retinoic acid alters the proliferation and survival of the epithelium and mesenchyme and suppresses Wnt/β-catenin signaling in developing cleft palate

Retinoic acid (RA) contributes to cleft palate; however, the cellular and molecular mechanisms responsible for the deleterious effects on the developing palate are unclear. Wnt signaling is a candidate pathway in the cleft palate and is associated with RA in organ development; thus, we aim to invest...

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Detalles Bibliográficos
Autores principales: Hu, X, Gao, J, Liao, Y, Tang, S, Lu, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920929/
https://www.ncbi.nlm.nih.gov/pubmed/24176856
http://dx.doi.org/10.1038/cddis.2013.424