Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration

Axonal degeneration often leads to the death of neuronal cell bodies. Previous studies demonstrated the crucial role of nicotinamide mononucleotide adenylyltransferase (Nmnat) 1, 2, and 3 in axonal protection. In this study, Nmnat3 immunoreactivity was observed inside axons in the optic nerve. Overe...

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Detalles Bibliográficos
Autores principales: Kitaoka, Y, Munemasa, Y, Kojima, K, Hirano, A, Ueno, S, Takagi, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920931/
https://www.ncbi.nlm.nih.gov/pubmed/24136224
http://dx.doi.org/10.1038/cddis.2013.391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920931/
https://www.ncbi.nlm.nih.gov/pubmed/24136224
http://dx.doi.org/10.1038/cddis.2013.391

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