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Light-controlled inhibition of malignant glioma by opsin gene transfer

Glioblastomas are aggressive cancers with low survival rates and poor prognosis because of their highly proliferative and invasive capacity. In the current study, we describe a new optogenetic strategy that selectively inhibits glioma cells through light-controlled membrane depolarization and cell d...

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Detalles Bibliográficos
Autores principales: Yang, F, Tu, J, Pan, J-Q, Luo, H-L, Liu, Y-H, Wan, J, Zhang, J, Wei, P-F, Jiang, T, Chen, Y-H, Wang, L-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920933/
https://www.ncbi.nlm.nih.gov/pubmed/24176851
http://dx.doi.org/10.1038/cddis.2013.425