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Zinc chelation: a metallothionein 2A's mechanism of action involved in osteosarcoma cell death and chemotherapy resistance

Osteosarcoma is the most common primary tumor of bone occurring in children and adolescents. The histological response to chemotherapy represents a key clinical factor related to survival. We previously showed that statins exhibit antitumor effects in vitro, inducing apoptotic cell death, reducing c...

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Detalles Bibliográficos
Autores principales: Habel, N, Hamidouche, Z, Girault, I, Patiño-García, A, Lecanda, F, Marie, P J, Fromigué, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920934/
https://www.ncbi.nlm.nih.gov/pubmed/24157868
http://dx.doi.org/10.1038/cddis.2013.405