Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila

Loss of the cell polarity gene could cooperate with oncogenic Ras to drive tumor growth and invasion, which critically depends on the c-Jun N-terminal Kinase (JNK) signaling pathway in Drosophila. By performing a genetic screen, we have identified Src42A, the ortholog of mammalian Src, as a key modu...

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Detalles Bibliográficos
Autores principales: Ma, X, Shao, Y, Zheng, H, Li, M, Li, W, Xue, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920939/
https://www.ncbi.nlm.nih.gov/pubmed/24136228
http://dx.doi.org/10.1038/cddis.2013.392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920939/
https://www.ncbi.nlm.nih.gov/pubmed/24136228
http://dx.doi.org/10.1038/cddis.2013.392

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