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Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila
Loss of the cell polarity gene could cooperate with oncogenic Ras to drive tumor growth and invasion, which critically depends on the c-Jun N-terminal Kinase (JNK) signaling pathway in Drosophila. By performing a genetic screen, we have identified Src42A, the ortholog of mammalian Src, as a key modu...
Autores principales: | Ma, X, Shao, Y, Zheng, H, Li, M, Li, W, Xue, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920939/ https://www.ncbi.nlm.nih.gov/pubmed/24136228 http://dx.doi.org/10.1038/cddis.2013.392 |
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