Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance

Radioresistance is a major challenge in prostate cancer (CaP) radiotherapy (RT). In this study, we investigated the role and association of epithelial–mesenchymal transition (EMT), cancer stem cells (CSCs) and the PI3K/Akt/mTOR signaling pathway in CaP radioresistance. We developed three novel CaP r...

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Detalles Bibliográficos
Autores principales: Chang, L, Graham, P H, Hao, J, Ni, J, Bucci, J, Cozzi, P J, Kearsley, J H, Li, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920940/
https://www.ncbi.nlm.nih.gov/pubmed/24157869
http://dx.doi.org/10.1038/cddis.2013.407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920940/
https://www.ncbi.nlm.nih.gov/pubmed/24157869
http://dx.doi.org/10.1038/cddis.2013.407

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