The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition of lens epithelial cells

Proliferation and epithelial–mesenchymal transition (EMT) of lens epithelium cells (LECs) may contribute to anterior subcapsular cataract (ASC) and posterior capsule opacification (PCO), which are important causes of visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanism has a...

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Detalles Bibliográficos
Autores principales: Chen, X, Xiao, W, Chen, W, Luo, L, Ye, S, Liu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920942/
https://www.ncbi.nlm.nih.gov/pubmed/24157878
http://dx.doi.org/10.1038/cddis.2013.416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920942/
https://www.ncbi.nlm.nih.gov/pubmed/24157878
http://dx.doi.org/10.1038/cddis.2013.416

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