Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription

Filopodia, which are actin-rich finger-like membrane protrusions, have an important role in cell migration and tumor metastasis. Here we identify 13 novel calumenin (Calu) isoforms (Calu 3–15) produced by alternative splicing, and find that Calu-15 promotes filopodia formation and cell migration. Ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, H, Chen, L, Wang, Q, Shen, B, Liu, L, Zheng, P, Xu, S, Liu, X, Chen, J, Teng, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920949/
https://www.ncbi.nlm.nih.gov/pubmed/24136234
http://dx.doi.org/10.1038/cddis.2013.403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920949/
https://www.ncbi.nlm.nih.gov/pubmed/24136234
http://dx.doi.org/10.1038/cddis.2013.403

Ejemplares similares