miR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injury

MicroRNAs (miRNAs) have a role in the cellular defense mechanism. Nuclear factor erythroid-2-related factor 2 (Nrf2) increases antioxidant enzyme capacity. However, miRNA transcriptionally controlled by Nrf2 had been uncharacterized. Here we report that miR-125b is transactivated by Nrf2 and inhibit...

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Detalles Bibliográficos
Autores principales: Joo, M S, Lee, C G, Koo, J H, Kim, S G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920955/
https://www.ncbi.nlm.nih.gov/pubmed/24176857
http://dx.doi.org/10.1038/cddis.2013.427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920955/
https://www.ncbi.nlm.nih.gov/pubmed/24176857
http://dx.doi.org/10.1038/cddis.2013.427

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