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Implication of transcriptional repression in compound C-induced apoptosis in cancer cells

Compound C, a well-known inhibitor of AMP-activated protein kinase (AMPK), has been reported to induce apoptosis in some types of cells. However, the underlying mechanisms remain largely unclear. Using a DNA microarray analysis, we found that the expression of many genes was downregulated upon treat...

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Detalles Bibliográficos
Autores principales: Dai, R Y, Zhao, X F, Li, J J, Chen, R, Luo, Z L, Yu, L X, Chen, S K, Zhang, C Y, Duan, C Y, Liu, Y P, Feng, C H, Xia, X M, Li, H, Fu, J, Wang, H Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920957/
https://www.ncbi.nlm.nih.gov/pubmed/24157877
http://dx.doi.org/10.1038/cddis.2013.419