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Field cancerization in the colon: a role for aberrant DNA methylation?

Colorectal cancer is the third most common cancer worldwide and arises secondary to the progressive accumulation of genetic and epigenetic alterations in normal colon cells, which results in a polyp-to-cancer progression sequence. It is known that individuals with a personal history of colon adenoma...

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Detalles Bibliográficos
Autores principales: Luo, Yanxin, Yu, Ming, Grady, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920999/
https://www.ncbi.nlm.nih.gov/pubmed/24760232
http://dx.doi.org/10.1093/gastro/got039