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Contribution of Orb2A Stability in Regulated Amyloid-Like Oligomerization of Drosophila Orb2

How learned experiences persist as memory for a long time is an important question. In Drosophila the persistence of memory is dependent upon amyloid-like oligomers of the Orb2 protein. However, it is not clear how the conversion of Orb2 to the amyloid-like oligomeric state is regulated. The Orb2 ha...

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Detalles Bibliográficos
Autores principales: White-Grindley, Erica, Li, Liying, Mohammad Khan, Repon, Ren, Fengzhen, Saraf, Anita, Florens, Laurence, Si, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921104/
https://www.ncbi.nlm.nih.gov/pubmed/24523662
http://dx.doi.org/10.1371/journal.pbio.1001786