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A Genome-Wide “Pleiotropy Scan” Does Not Identify New Susceptibility Loci for Estrogen Receptor Negative Breast Cancer

Approximately 15–30% of all breast cancer tumors are estrogen receptor negative (ER−). Compared with ER-positive (ER+) disease they have an earlier age at onset and worse prognosis. Despite the vast number of risk variants identified for numerous cancer types, only seven loci have been unambiguously...

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Detalles Bibliográficos
Autores principales: Campa, Daniele, Barrdahl, Myrto, Tsilidis, Konstantinos K., Severi, Gianluca, Diver, W. Ryan, Siddiq, Afshan, Chanock, Stephen, Hoover, Robert N., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick R., Le Marchand, Loïc, Flesch-Janys, Dieter, Lindström, Sara, Hunter, David J., Hankinson, Susan E., Willett, Walter C., Kraft, Peter, Cox, David G., Khaw, Kay-Tee, Tjønneland, Anne, Dossus, Laure, Trichopoulos, Dimitrios, Panico, Salvatore, van Gils, Carla H., Weiderpass, Elisabete, Barricarte, Aurelio, Sund, Malin, Gaudet, Mia M., Giles, Graham, Southey, Melissa, Baglietto, Laura, Chang-Claude, Jenny, Kaaks, Rudolf, Canzian, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921107/
https://www.ncbi.nlm.nih.gov/pubmed/24523857
http://dx.doi.org/10.1371/journal.pone.0085955