Targeted Inhibition of FAK, PYK2 and BCL-XL Synergistically Enhances Apoptosis in Ovarian Clear Cell Carcinoma Cell Lines

Ovarian clear cell carcinoma (OCCC) displays a higher resistance to first line chemotherapy, requiring the development of new therapeutics. We previously identified a frequent chromosomal gain at 8q24 that harbors the focal-adhesion kinase (FAK) gene; the potential of this gene as a therapeutic targ...

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Detalles Bibliográficos
Autores principales: Yoon, Heejei, Choi, Yoon-La, Song, Ji-Young, Do, Ingu, Kang, So Young, Ko, Young-Hyeh, Song, Sangyong, Kim, Byoung-Gie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921183/
https://www.ncbi.nlm.nih.gov/pubmed/24523919
http://dx.doi.org/10.1371/journal.pone.0088587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921183/
https://www.ncbi.nlm.nih.gov/pubmed/24523919
http://dx.doi.org/10.1371/journal.pone.0088587

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