Combined Pharmacological Induction of Hsp70 Suppresses Prion Protein Neurotoxicity in Drosophila

Prion diseases are rare and aggressive neurodegenerative disorders caused by the accumulation of misfolded, toxic conformations of the prion protein (PrP). Therapeutic strategies directed at reducing the levels of PrP offer the best chance of delaying or halting disease progression. The challenge, t...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Casas-Tinto, Sergio, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921213/
https://www.ncbi.nlm.nih.gov/pubmed/24523910
http://dx.doi.org/10.1371/journal.pone.0088522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921213/
https://www.ncbi.nlm.nih.gov/pubmed/24523910
http://dx.doi.org/10.1371/journal.pone.0088522

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