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Biomarker Evidence of Axonal Injury in Neuroasymptomatic HIV-1 Patients

BACKGROUND: Prevalence of neurocognitive impairment in HIV-1 infected patients is reported to be high. Whether this is a result of active HIV-related neurodegeneration is unclear. We examined axonal injury in HIV-1 patients by measuring the light subunit of neurofilament protein (NFL) in CSF with a...

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Detalles Bibliográficos
Autores principales: Jessen Krut, Jan, Mellberg, Tomas, Price, Richard W., Hagberg, Lars, Fuchs, Dietmar, Rosengren, Lars, Nilsson, Staffan, Zetterberg, Henrik, Gisslén, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921217/
https://www.ncbi.nlm.nih.gov/pubmed/24523921
http://dx.doi.org/10.1371/journal.pone.0088591