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Simultaneous Characterization of Somatic Events and HPV-18 Integration in a Metastatic Cervical Carcinoma Patient Using DNA and RNA Sequencing

OBJECTIVE: Integration of carcinogenic human papillomaviruses (HPVs) into the host genome is a significant tumorigenic factor in specific cancers including cervical carcinoma. Although major strides have been made with respect to HPV diagnosis and prevention, identification and development of effica...

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Detalles Bibliográficos
Autores principales: Liang, Winnie S., Aldrich, Jessica, Nasser, Sara, Kurdoglu, Ahmet, Phillips, Lori, Reiman, Rebecca, McDonald, Jacquelyn, Izatt, Tyler, Christoforides, Alexis, Baker, Angela, Craig, Christine, Egan, Jan B., Chase, Dana M., Farley, John H., Bryce, Alan H., Stewart, A. Keith, Borad, Mitesh J., Carpten, John D., Craig, David W., Monk, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921261/
https://www.ncbi.nlm.nih.gov/pubmed/24418928
http://dx.doi.org/10.1097/IGC.0000000000000049