Cargando…

CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules under normoxic and hypoxic conditions in vitro: the importance of CX3CR1 signaling

OBJECTIVE: Inflammation and hypoxia activate the fractalkine (CX3CL1) receptor (CX3CR1)-related signaling pathway. Tumor necrosis factor alpha (TNFα) induces CX3CL1, influencing a mechanism of CX3CL1 autoregulation by CX3CR1 expression. We compared spontaneous and lipopolysaccharide (LPS)-induced CX...

Descripción completa

Detalles Bibliográficos
Autores principales: Szukiewicz, Dariusz, Kochanowski, Jan, Mittal, Tarun Kumar, Pyzlak, Michal, Szewczyk, Grzegorz, Cendrowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921448/
https://www.ncbi.nlm.nih.gov/pubmed/24270813
http://dx.doi.org/10.1007/s00011-013-0687-z