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CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules under normoxic and hypoxic conditions in vitro: the importance of CX3CR1 signaling
OBJECTIVE: Inflammation and hypoxia activate the fractalkine (CX3CL1) receptor (CX3CR1)-related signaling pathway. Tumor necrosis factor alpha (TNFα) induces CX3CL1, influencing a mechanism of CX3CL1 autoregulation by CX3CR1 expression. We compared spontaneous and lipopolysaccharide (LPS)-induced CX...
Autores principales: | Szukiewicz, Dariusz, Kochanowski, Jan, Mittal, Tarun Kumar, Pyzlak, Michal, Szewczyk, Grzegorz, Cendrowski, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921448/ https://www.ncbi.nlm.nih.gov/pubmed/24270813 http://dx.doi.org/10.1007/s00011-013-0687-z |
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