Ectopic A-lattice seams destabilize microtubules

Natural microtubules typically include one A-lattice seam within an otherwise helically symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule dynamic instability. Here we find that including extra A-lattice seams in GMPCPP microtubules, structural analogues of t...

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Detalles Bibliográficos
Autores principales: Katsuki, Miho, Drummond, Douglas R., Cross, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921467/
https://www.ncbi.nlm.nih.gov/pubmed/24463734
http://dx.doi.org/10.1038/ncomms4094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921467/
https://www.ncbi.nlm.nih.gov/pubmed/24463734
http://dx.doi.org/10.1038/ncomms4094

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